Overcoming Drug Resistant Melanoma

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Researchers at the Technion-Israel Institute of Technology have suggested a new approach to overcoming anticancer-drug resistance in melanoma based on the discovery of  two proteins that together play together a major role in the phenomenon.

The research, published in the Journal of Investigative Dermatology, was headed by Prof. Amir Orian (head of the lab for the study of genetic networks at the Faculty of Medicine and a member of the Technion’s Integrated Cancer Research Center of the Technion’s Rapaport Faculty of Medicine) and Dr. Emily Avitan-Hersh (a lecturer in the Technion’s Faculty of Medicine and deputy director of the dermatology department and a member of the Rambam Clinical Research Institute at Rambam Medical Center), in collaboration with Prof. Ze’ev A. Ronai of the Sanford Burnham Prebys Medical Discovery Institute in California.

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In Heart Micro-computers

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Vectorius Medical’s V-LAP Left Atrial Filling Pressure Sensor, Image Credit: Vectorius Medical

TAKE HEART: Every year, millions of adults worldwide are diagnosed with heart failure. Vectorious’ V-LAP, the world’s first direct heart pressure monitor located on the heart’s left atrium, is allowing physicians to get unprecedented access to the earliest indication of heart pressure changes before the patient feels any symptoms, in order to manage the disease and to live a better life.

Vectorius co-founders, Oren Goldshtein and Dr. Eyal Orion, are both Technion Alumni.

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New Quantum Microscope

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Prof. Ido Kaminer of Technion-Israel Institute of Technology’s Andrew and Erna Viterbi Faculty of Electrical Engineering heads the Robert and Ruth Magid Electron Beam Quantum Dynamics Lab. His AdQuanta group has developed a new 4D electron microscope, the first of it’s kind in Israel and one of the few in the world.

This breakthrough is likely to have an impact on numerous potential applications, including the design of new quantum materials for storing quantum bits with greater stability. Similarly, it can help improve the sharpness of colors on cell phones and other kinds of screens.

Kaminer explains, “We have developed an electron microscope that produces, what is in many respects, the best near- field optical microscopy in the world. Using our microscope, we can change the color and angle of light that illuminates any sample of nano materials and map their interactions with electrons, as we demonstrated with photonic crystals.”

 

Tech for N95 Masks

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Prof. Yair Ein-Eli, dean of the Faculty of Materials Science and Engineering at the Technion. Photo: courtesy

Researchers Develop Self-cleaning Face Mask Which Could Kill Coronavirus

Led by Professor Yair Ein-Eli, researchers from the Technion Faculty of Materials Science and Engineering have developed a self-disinfecting, reusable protective face mask.

The disinfection process occurs when a layer of carbon fibers in the mask is heated using a low current source, such as a mobile phone charger. A patent application for the invention has been submitted in the U.S.

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Touchless Access in a Post-COVID World

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Sonorax CCO Nimrod May

Israeli startup Sonarax is ready for a touchless new world with its ready-to-install ultrasonic data-transmission technology.  In the era of COVID, we are all more of shared touch surfaces such as elevator buttons, ATM touch pads and other buttons touched by multiple people. Sonarax offers a touchless solution based on machine-to-machine technology using sound-waves to transfer data between any devices equipped with a speaker and microphone.

“It all began with Roni Papo, an engineer from the Technion, who had the vision and passion to harness sound-waves in order to deliver data,” says Sonarax Chief Commercial Officer Nimrod May.  “He developed algorithms to send data in small packages over soundwaves.”

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Le génie médical au Technion

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Dr. David Bensoussan

Nous sommes fier de partager cette article, écrit par David Bensoussan, un ancien de Technion, qui examine les avances réalisé par les graduées et chercheurs du Technion. Présentée cette semaine dans Times of Israel.

Examine les nombreuses avances réalisées par les techniciens et les anciens.

We are proud to share this article written by Technion alumnus, David Bensoussan, which explores the medical advances achieved by Technion researchers and alumni.  Featured this week in the Times of Israel.  

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Protecting Medical Workers from COVID-19

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New High-Tech Sticker Improves the Effectiveness of Surgical Masks and Protects Medical Staff against COVID-19

Prof. Eyal Zussman of the Faculty of Mechanical Engineering at Technion and the COVID-19 National Emergency Team of the Defense Ministry’s Directorate of Defense R&D (DDR&D) have developed a unique sticker that can be affixed to surgical masks and renders them more effective. The sticker was developed in conjunction with the Galilee Medical Center in Nahariya. The new device will reduce the instances of infection and provide improved protection for the medical staff.

Prof. Zussman is the head of the Nano-Engineering Lab in the Faculty of Mechanical Engineering. Together with the lab team, he developed a unique sticker that is affixed to standard surgical masks and improves their effectiveness. The sticker, named ‘Maya,’ is manufactured using a 3D printer and consists of nanometric fibers coated with antiseptics – which improves the trapping of nanometric particles and efficiently neutralizes viruses from droplets that might reach the mask.

The sticker was developed in partnership with scientists from the Chemical and Biological Section of the DDR&D, led by Dr. Dan Greenstein in partnership with Prof. Samer Srouji, Director of Oral Surgery at the Galilee Medical Center in Nahariya.

The Ministry of Health has granted the ‘Maya’ sticker a preliminary approval and in upcoming days a pilot project will begin at the Galilee Medical Center to assess the adaptability of the medical staff to the sticker. Dr. Masad Barhoum, General Director of the Galilee Medical Center, thanked the Ministry of Defense and Technion for the fruitful collaboration and expressed his hope that the new sticker will reduce the incidence of COVID-19 infection among the medical staff. “This is an available and fast solution based on sophisticated technology. We hope that the pilot project will succeed and that this unique innovation will be introduced to many other hospitals around the country,” said Srouji.

The COVID-19 National Emergency Team continues to search for and develop advanced technologies that will help fight the spread of the virus. The Team is adapting defense technologies to civil applications. They are working around the clock in order to swiftly bring tested solutions to answer the critical needs of the hospitals.

SUPPORT THE COVID-19 EMERGENCY RESEARCH FUND

Solving Antibiotic Resistance

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Nanosynex Co-founders Michelle Heymann and Diane Abensur Bessin

Medical start-up Nanosynex was founded by CEO Diane Abensur and VP marketing and business development Michelle Heymann, who met when they were studying for MBAs at the Technion.  Both had recently immigrated to Israel; Abensur from France and Heymann from Brazil.

Based on findings by renowned Technion-Israel Institute of Technology cell researcher Prof. Shulamit Levenberg, Nanosynex  has developed a method of precisely adapting antibiotics to infections. The objective is to implement more effective and faster treatment without encouraging the resistance of bacteria to the most widely used antibiotics.

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National Inventor’s Day

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“Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world.” – Albert Einstein, Founder of the first Technion Society.

When knowledge meets imagination, innovation is born. After all, how can one create something new without thinking outside of the box?

The Technion is know world-wide for its cutting edge innovation, so it’s only fitting that we celebrate some of Technion’s most exciting inventors in honour of National Inventor’s Day on February 11th.

 Sniffphone

Prof. Hossam Haick of Technion’s Wolfson Faculty of Chemical Engineering presents SNIFFPHONE, a Horizon 2020 EU project that has harnessed nanotechnology, (bio)chemistry, materials engineering, process engineering, biomedical engineering, electrical engineering, and medicine to develop and test a miniaturized system that relies on an artificially intelligent nano-array for an inexpensive, fast, non-invasive detection of gastric cancer via exhaled breath.  

The USB key

Technion alumnus Dov Moran is an entrepreneur and investor. But what he is best known for is his invention which changed the world, the USB flash drive. With this invention, massive amounts of information can be transported in your pocket from one computer to the next. Used by everyone from CEOs to DJs, this little stick has a huge impact on the way we move data.

 Scarless Surgery

Kobi Vortman graduated from Technion with a vision. His work led him to create InSightec, which destroys tumors by using ultrasound. No incisions means no scars, a reduced risk of infection and less time for post-operative healing. This innovative biotechnology “cooks” tumors to death without harming the body.

Sealantis

Sealantis develops medical device products, based on a proprietary platform of alga-mimetic tissue adhesives, for a variety of applications in surgical adhesion. The company was established through the AMIT Institute at the Technion, under the leadership of Prof. Havazelet Bianco-Peled, a world-renowned expert in biomedical polymers, from the Faculty of Chemical Engineering at the Technion.  The company’s present focus is on surgical seals designed to stop bleeding, prevent leakage of digestive tract contents into the abdominal cavity, prevent leakage of spinal fluid, and a variety of other applications.

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Lempel-Ziv Algorithm

40 years ago, Profs. Abraham Lempel and Jacob Ziv of Technion’s Faculty of Computer Science started something remarkable. They discovered the math behind the internet and the legendary Lempel-Ziv Algorithm was born. Now known as the international standard for data compression, their invention is the reason you’re able to read this article right now.

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Life-saving Tissue

Prof. Shulamit Levenberg, Dean of Technion’s Faculty of Biomedical Engineering and Prof. Lior Gepstein, of Technion’s Faculty of Medicine, make quite the team. This dynamic duo is changing the field of regenerative medicine. Using human embryonic stem cells, they can create artificial tissue to create a new heart muscle with its own blood supply. Through new and innovative 3D printing technology, it is now possible to replace cardiac tissue damaged by the patient’s heart disease.

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Surgical Snake Robot

Professor Alon Wolf  is a leading robotics researcher and also serves as Vice President, External Relations & Resource Development at the Technion. His invention, the Snake Robot, is a snake-like device controlled by surgeons that enters a patient’s body without incision to locate the area requiring treatment. Thanks to this invention, many patients can avoid complications such as trauma, risk of infection and decreases rates of hospitalization – an important advancement in the field of surgical medicine.

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Baby Monitor of the 21st century

Dr. Assaf Glazer completed his Ph.D. at the Technion, specialized in the fields of machine learning and computer vision, and later worked as a post-doctorate in the Runway Program at the Jacobs Institute at Cornell-Tech.  Today, Glazer is the CEO and Founder of Nanit – a company creating smart baby monitors that use machine learning algorithms to provide sleep insights through first-of-its-kind camera vision. Nanit even made CNBC’s most promising startups list!

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Machine Learning Cancer Treatment

Prof. Yuval Shaked has quite a few titles under his belt, as well as grants, awards and research papers. Currently, he is the head of the Technion’s Integrated Cancer Center and has been leading a research project which led to creation of Oncohost. Oncohost is a personalized cancer treatment which uses machine learning to characterize, analyze and predict a patient’s response to treatment.

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Technion’s students, teachers and alumni come together every day to deliver innovations and inventions that change our world. They lead by example, teaching us that when a problem arises you need to think creatively and outside the box to solve it.

Contribute to tomorrow’s innovation and help aspiring inventors make our world a better place. Direct your support to Entrepreneurship & Innovation through the Technion Fund.

Nanochips Deliver Alzheimer’s Therapy to the Brain

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Researchers at the Technion, led by Professor Ester Segal of the Faculty of Biotechnology and Food Engineering, and researchers at Bar Ilan University, have developed new technology for transporting drugs within silicon nanostructures to the brain.

These nanostructures release an essential protein, which can inhibit the development of Alzheimer’s disease, and provide targeted delivery in the brain with the use of a “gene gun.” The research was conducted with the support of the Russell Berrie Nanotechnology Institute at the Technion.

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